The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes.

A translocation involving human chromosome 10, band q24, in a subset of T-cell acute leukemias disrupts a region surrounding the putative oncogene HOX11, which encodes a protein with a homeodomain. The HOX11 protein binds to a specific DNA sequence, it localizes to the cell nucleus, and it transacti...

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Main Authors: T. Neil Dear, Isidro Sánchez‐García, Terence H. Rabbitts
格式: Artigo
语言:英语
出版: 1993
在线阅读:https://doi.org/10.1073/pnas.90.10.4431
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