The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes.
A translocation involving human chromosome 10, band q24, in a subset of T-cell acute leukemias disrupts a region surrounding the putative oncogene HOX11, which encodes a protein with a homeodomain. The HOX11 protein binds to a specific DNA sequence, it localizes to the cell nucleus, and it transacti...
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Main Authors: | , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
1993
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在线阅读: | https://doi.org/10.1073/pnas.90.10.4431 |
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