The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice
Autophagy is an evolutionarily conserved bulk-protein degradation pathway in which isolation membranes engulf the cytoplasmic constituents, and the resulting autophagosomes transport them to lysosomes. Two ubiquitin-like conjugation systems, termed Atg12 and Atg8 systems, are essential for autophago...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2008
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| Online Access: | https://doi.org/10.1091/mbc.e08-03-0309 |
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