The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice

The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice

Autophagy is an evolutionarily conserved bulk-protein degradation pathway in which isolation membranes engulf the cytoplasmic constituents, and the resulting autophagosomes transport them to lysosomes. Two ubiquitin-like conjugation systems, termed Atg12 and Atg8 systems, are essential for autophago...

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Main Authors: Yu‐shin Sou, Satoshi Waguri, J. Iwata, Takashi Ueno, Tsutomu Fujimura, Taichi Hara, Naoki Sawada, Akane Yamada, Noboru Mizushima, Yasuo Uchiyama, Eiki Kominami, Keiji Tanaka, Masaaki Komatsu
Format: Artigo
Jezik:angleščina
Izdano: 2008
Online dostop:https://doi.org/10.1091/mbc.e08-03-0309
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