Design, Synthesis, Antinociceptive and Anti-Inflammatory Activities of Novel Piroxicam Analogues

In this paper we report the design, synthesis, antinociceptive and anti-inflammatory activities of a series of benzothiazine N-acylhydrazones 14a–h, planned by structural modification of piroxicam (1), a non steroidal anti-inflammatory drug. Among the synthesized analogues, compounds 14f (LASSBio-16...

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Main Authors: Amanda Silva de Miranda, Walfrido Bispo Júnior, Yolanda Silva, Magna Suzana Alexandre‐Moreira, Rosane Nora Castro, J.R. Sabino, Luciano M. Lião, Lı́dia Moreira Lima, Eliezer J. Barreiro
格式: Artigo
语言:英语
出版: 2012
在线阅读:https://doi.org/10.3390/molecules171214126
https://www.mdpi.com/1420-3049/17/12/14126/pdf?version=1403114337
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