Cell culture and<i>Drosophila</i>model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma

Cell culture and<i>Drosophila</i>model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma

Summary Neuroblastoma is a childhood extracranial solid tumor which is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the Anaplastic Lymphoma Kinase (ALK) receptor tyrosine kinase (RTK), which have been found in both somatic a...

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Main Authors: Damini Chand, Yasuo Yamazaki, Kristina Ruuth, Christina Schönherr, Tommy Martinsson, Per Kogner, Edward F. Attiyeh, John M. Maris, Olena Morozova, Marco A. Marra, Miki Ohira, Akira Nakagawara, Per‐Erik Sandström, Ruth H. Palmer, Bengt Hallberg
Format: Artigo
Jezik:angleščina
Izdano: 2012
Online dostop:https://doi.org/10.1242/dmm.010348
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https://doi.org/10.1242/dmm.010348

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