Cell culture and<i>Drosophila</i>model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma
Summary Neuroblastoma is a childhood extracranial solid tumor which is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the Anaplastic Lymphoma Kinase (ALK) receptor tyrosine kinase (RTK), which have been found in both somatic a...
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| Auteurs principaux: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2012
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| Accès en ligne: | https://doi.org/10.1242/dmm.010348 |
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