Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

Membrane CD36 functions in the uptake of fatty acids (FAs), oxidized lipoproteins and in signal transduction after binding these ligands. In rodents, CD36 is implicated in abnormal lipid metabolism, inflammation and atherosclerosis. In humans, CD36 variants have been identified to influence free FA...

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Main Authors: Latisha Love‐Gregory, Richard Sherva, Timothy Schappe, Jian-Shen Qi, Jennifer McCrea, Samuel Klein, Margery A. Connelly, Nada A. Abumrad
格式: Artigo
语言:英语
出版: 2010
在线阅读:https://doi.org/10.1093/hmg/ddq449
https://academic.oup.com/hmg/article-pdf/20/1/193/17252119/ddq449.pdf
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