Memory CD8+ T Cells Require CD28 Costimulation

Abstract CD8+ T cells are a critical component of the adaptive immune response against infections and tumors. A current paradigm in immunology is that naive CD8+ T cells require CD28 costimulation, whereas memory CD8+ T cells do not. We show here, however, that during viral infections of mice, costi...

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Hlavní autoři: Annie B. Borowski, Alina C. Boesteanu, Yvonne M. Mueller, Caterina Carafides, David J. Topham, John D. Altman, Stephen R. Jennings, Peter D. Katsikis
Médium: Artigo
Jazyk:angličtina
Vydáno: 2007
On-line přístup:https://doi.org/10.4049/jimmunol.179.10.6494
https://journals.aai.org/jimmunol/article-pdf/179/10/6494/1245361/zim02207006494.pdf
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