Memory CD8+ T Cells Require CD28 Costimulation
Abstract CD8+ T cells are a critical component of the adaptive immune response against infections and tumors. A current paradigm in immunology is that naive CD8+ T cells require CD28 costimulation, whereas memory CD8+ T cells do not. We show here, however, that during viral infections of mice, costi...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2007
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| Online Access: | https://doi.org/10.4049/jimmunol.179.10.6494 https://journals.aai.org/jimmunol/article-pdf/179/10/6494/1245361/zim02207006494.pdf |
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