Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes

The high incidence of sudden death in heart failure may reflect abnormalities of repolarization and heightened susceptibility to arrhythmogenic early afterdepolarizations (EADs). We hypothesized that overexpression of the human K+ channel HERG (human ether-a-go-go-related gene) could enhance repolar...

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Main Authors: Hanne Nuss, Eduardo Marbán, David C. Johns
格式: Artigo
语言:英语
出版: 1999
在线阅读:https://doi.org/10.1172/jci5073
http://www.jci.org/articles/view/5073/files/pdf
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