Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3β pathway in isolated aging rat hearts

The physiological and pathological roles of hydrogen sulfide (H2S) in the regulation of cardiovascular functions have been recognized. Cystathionine gamma-lyase (CSE) is a major H2S-producing enzyme in cardiovascular system. Ischemic post-conditioning (PC) provides cadioprotection in young hearts bu...

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Main Authors: Hongzhu Li, Yuehong Wang, Can Wei, Shuzhi Bai, Yajun Zhao, Hongxia Li, Bo Wu, Rui Wang, Lingyun Wu, Changqing Xu
格式: Artigo
语言:英语
出版: 2015
在线阅读:https://doi.org/10.1186/s13578-015-0003-4
https://cellandbioscience.biomedcentral.com/counter/pdf/10.1186/s13578-015-0003-4
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