T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6
An important signaling pathway for the differentiation of T helper type 2 (TH2) cells from uncommitted CD4 T cell precursors is activation of the STAT6 transcription factor by interleukin 4 (IL-4). The protooncogene BCL-6 is also involved in TH2 differentiation, as BCL-6 −/− mice develop an inflamma...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
1998
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| 在线阅读: | https://doi.org/10.1073/pnas.95.23.13823 |
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