T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6
An important signaling pathway for the differentiation of T helper type 2 (TH2) cells from uncommitted CD4 T cell precursors is activation of the STAT6 transcription factor by interleukin 4 (IL-4). The protooncogene BCL-6 is also involved in TH2 differentiation, as BCL-6 −/− mice develop an inflamma...
Sparad:
| Huvudupphovsmän: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | engelska |
| Publicerad: |
1998
|
| Länkar: | https://doi.org/10.1073/pnas.95.23.13823 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|