Tumor Growth Rate Is an Early Indicator of Antitumor Drug Activity in Phase I Clinical Trials

Abstract Purpose: Response Evaluation Criteria in Solid Tumors (RECIST) evaluation does not take into account the pretreatment tumor kinetics and may provide incomplete information about experimental drug activity. Tumor growth rate (TGR) allows for a dynamic and quantitative assessment of the tumor...

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Main Authors: Charles Ferté, Marianna Fernandez, Antoine Hollebecque, Serge Koscielny, Antonin Lévy, Christophe Massard, Rastislav Balheda, Brian M. Bot, Carlos Gomez‐Roca, Clarisse Dromain, Samy Ammari, Jean‐Charles Soria
格式: Artigo
语言:英语
出版: 2013
在线阅读:https://doi.org/10.1158/1078-0432.ccr-13-2098
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