Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus.
To examine T cell receptor (TCR) diversity involved in the memory response to a persistent human pathogen, we determined nucleotide sequences encoding TCR-alpha and -beta chains from HLA-B8-restricted, CD8+ cytotoxic T cell clones specific for an immunodominant epitope (FLRGRAYGL) in Epstein-Barr vi...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Sprog: | engelsk |
Udgivet: |
1994
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Online adgang: | https://doi.org/10.1084/jem.180.6.2335 https://rupress.org/jem/article-pdf/180/6/2335/1106094/2335.pdf |
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