Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment

Eitemau Tebyg

• Reactive Oxygen Species Mediate p53 Activation and Apoptosis Induced by Sodium Nitroprusside in SH-SY5Y Cells
  gan: Simone Cardaci, et al.
  Cyhoeddwyd: (2008)
• p38MAPK and ERK1/2 dictate cell death/survival response to different pro-oxidant stimuli via p53 and Nrf2 in neuroblastoma cells SH-SY5Y
  gan: Giuseppe Filomeni, et al.
  Cyhoeddwyd: (2012)
• The isatin-Schiff base copper(II) complex Cu(isaepy) 2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis
  gan: Giuseppe Filomeni, et al.
  Cyhoeddwyd: (2009)
• The isatin-Schiff base copper(II) complex Cu(isaepy)(2) acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis
  gan: Filomeni, Giuseppe, et al.
  Cyhoeddwyd: (2009)
• Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells
  gan: Aquilano, Katia, et al.
  Cyhoeddwyd: (2010)