Canonical Wnt Signaling Induces Vascular Endothelial Dysfunction via p66 <sup>Shc</sup> -Regulated Reactive Oxygen Species
Objective— Reactive oxygen species regulate canonical Wnt signaling. However, the role of the redox regulatory protein p66 Shc in the canonical Wnt pathway is not known. We investigated whether p66 Shc is essential for canonical Wnt signaling in the endothelium and determined whether the canonical W...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2014
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| Online Access: | https://doi.org/10.1161/atvbaha.114.304338 |
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