Chemokine Receptor 4 Plays a Key Role in T Cell Recruitment into the Airways of Asthmatic Patients

T lymphocytes of the Th2 type are central orchestrators of airway inflammation in asthma. The mechanisms that regulate their accumulation in the asthmatic airways remains poorly understood. We tested the hypothesis that CCR4, preferentially expressed on T lymphocytes of the Th2 type, plays a critica...

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Main Authors: Pandurangan Vijayanand, Kesta Durkin, Guido Hartmann, Jaymin B. Morjaria, Grégory Seumois, Karl J. Staples, David A. Hall, Christina Bessant, Michelle A. Bartholomew, Peter Howarth, Peter S. Friedmann, Ratko Djukanović
Format: Artigo
Language:English
Published: 2010
Online Access:https://doi.org/10.4049/jimmunol.0901342
https://journals.aai.org/jimmunol/article-pdf/184/8/4568/1320586/ji_0901342.pdf
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