Targeting FLT3 to treat leukemia

Introduction: Approximately 23% of acute myeloid leukemia (AML) patients younger than 60 years of age carry a mutation in the transmembrane domain of the FMS-like tyrosine kinase-3 (FLT3) gene (FLT3/internal tandem duplications [ITD]). In normal karyotype AML, the presence of a FLT3/ITD mutation is...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Helmut König, Mark J. Levis
Hōputu: Revisão
Reo:Ingarihi
I whakaputaina: 2014
Urunga tuihono:https://doi.org/10.1517/14728222.2014.960843
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