Targeting FLT3 to treat leukemia

Introduction: Approximately 23% of acute myeloid leukemia (AML) patients younger than 60 years of age carry a mutation in the transmembrane domain of the FMS-like tyrosine kinase-3 (FLT3) gene (FLT3/internal tandem duplications [ITD]). In normal karyotype AML, the presence of a FLT3/ITD mutation is...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Helmut König, Mark J. Levis
Fformat: Revisão
Iaith:Saesneg
Cyhoeddwyd: 2014
Mynediad Ar-lein:https://doi.org/10.1517/14728222.2014.960843
Tagiau: Ychwanegu Tag
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