Study of Genotypic and Phenotypic HIV-1 Dynamics of Integrase Mutations During Raltegravir Treatment: A Refined Analysis by Ultra-Deep 454 Pyrosequencing
The dynamics of raltegravir-resistant variants and their impact on virologic response in 23 HIV-1-infected patients, who started a salvage raltegravir-containing regimen, were investigated.Integrase population sequencing and Ultra-Deep-454 Pyrosequencing (UDPS) were performed on plasma samples at ba...
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Hlavní autoři: | , , , , , , , , , , , , , , , , , , |
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Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
2012
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On-line přístup: | https://doi.org/10.1093/infdis/jir821 https://academic.oup.com/jid/article-pdf/205/4/557/18067371/jir821.pdf |
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