Study of Genotypic and Phenotypic HIV-1 Dynamics of Integrase Mutations During Raltegravir Treatment: A Refined Analysis by Ultra-Deep 454 Pyrosequencing

Study of Genotypic and Phenotypic HIV-1 Dynamics of Integrase Mutations During Raltegravir Treatment: A Refined Analysis by Ultra-Deep 454 Pyrosequencing

The dynamics of raltegravir-resistant variants and their impact on virologic response in 23 HIV-1-infected patients, who started a salvage raltegravir-containing regimen, were investigated.Integrase population sequencing and Ultra-Deep-454 Pyrosequencing (UDPS) were performed on plasma samples at ba...

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Bibliografiske detaljer
Main Authors: Daniele Armenia, Ina Vandenbroucke, Lavinia Fabeni, Herwig Van Marck, Valeria Cento, Roberta D’Arrigo, Liesbeth Van Wesenbeeck, Fernanda Scopelliti, Valeria Micheli, Bianca Bruzzone, Sergio Lo Caputo, Jeroen Aerssens, Giuliano Rizzardini, Valerio Tozzi, Pasquale Narciso, Andrea Antinori, Lieven Stuyver, Carlo Federico Perno, Francesca Ceccherini‐Silberstein
Format: Artigo
Sprog:engelsk
Udgivet: 2012
Online adgang:https://doi.org/10.1093/infdis/jir821
https://academic.oup.com/jid/article-pdf/205/4/557/18067371/jir821.pdf
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https://doi.org/10.1093/infdis/jir821
https://academic.oup.com/jid/article-pdf/205/4/557/18067371/jir821.pdf

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