Soluble CTLA-4 receptor an immunological marker of Graves' disease and severity of ophthalmopathy is associated with CTLA-4 Jo31 and CT60 gene polymorphisms

Objective Graves' disease (GD) is an autoimmune disorder with genetic and environmental background. CTLA-4 is a candidate gene for thyroid autoimmunity. Increased serum levels of soluble CTLA-4 (sCTLA-4) were found in some autoimmune diseases. Aim The aim of the study was to evaluate the relati...

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Main Authors: Jacek Daroszewski, Edyta Pawlak, Lidia Karabon, Irena Frydecka, Anna Jonkisz, Mirosław Słowik, Marek Bolanowski
Format: Artigo
Jezik:angleščina
Izdano: 2009
Online dostop:https://doi.org/10.1530/eje-09-0600
https://eje.bioscientifica.com/downloadpdf/journals/eje/161/5/787.pdf
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