YAP regulates cell proliferation, migration, and steroidogenesis in adult granulosa cell tumors

The Hippo signaling pathway has been implicated as a conserved regulator of organ size in both Drosophila and mammals. Yes-associated protein (YAP), the central component of the Hippo signaling cascade, functions as an oncogene in several malignancies. Ovarian granulosa cell tumors (GCT) are charact...

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Bibliographic Details
Main Authors: Zhenming Fu, Xiangmin Lv, Guohua Hua, Chunbo He, Jixin Dong, Subodh M. Lele, David Wan-Cheng Li, Qiong-Li Zhai, John S. Davis, Cheng Wang
Format: Artigo
Language:English
Published: 2014
Online Access:https://doi.org/10.1530/erc-13-0339
https://erc.bioscientifica.com/downloadpdf/journals/erc/21/2/297.pdf
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