Hypoxia-driven immunosuppression contributes to the pre-metastatic niche
Primary tumor cells create favorable microenvironments in secondary organs, termed pre-metastatic niches, that promote the formation of metastases. Using immune competent syngenic breast cancer mouse models, we have recently demonstrated that factors secreted by hypoxic tumor cells condition pre-met...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2012
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| 在线阅读: | https://doi.org/10.4161/onci.22355 |
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