The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic beta cells are killed by infiltrating immune cells and by cytokines released by these cells. Signaling events occurring in the pancreatic beta cells are decisive for their survival or death in diabetes. We have used RNA sequencing (R...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | 英语 |
出版: |
2012
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在線閱讀: | https://doi.org/10.1371/journal.pgen.1002552 https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002552&type=printable |
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