Telomeres and telomerase: A dual role in hepatocarcinogenesis

Telomere shortening limits the proliferative capacity of primary human cells and restrains the regenerative capacity of organ systems during chronic diseases and aging. Telomere shortening apparently has a dual role in tumor development and progression. On the one hand, it induces chromosomal instab...

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Main Authors: Satyanarayana Ande, Michael P. Manns, K. Lenhard Rudolph
格式: Revisão
语言:英语
出版: 2004
在线阅读:https://doi.org/10.1002/hep.20308
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.20308
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