ROS1 Immunohistochemistry for Detection of ROS1-Rearranged Lung Adenocarcinomas
ROS1 gene rearrangements are reported in 1% to 2% of lung adenocarcinomas (ACAs) and are associated with response to the multitargeted tyrosine kinase inhibitor crizotinib. ROS1 rearrangements can be detected using fluorescence in situ hybridization (FISH); however, immunohistochemistry (IHC) for RO...
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| Main Authors: | , , , , , , |
|---|---|
| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2013
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| 在线阅读: | https://doi.org/10.1097/pas.0b013e3182960fa7 |
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