Prevention of Plasticity of Endocannabinoid Signaling Inhibits Persistent Limbic Hyperexcitability Caused by Developmental Seizures
Depolarization-induced suppression of inhibition (DSI) is an endocannabinoid-mediated short-term plasticity mechanism that couples postsynaptic Ca 2+ rises to decreased presynaptic GABA release. Whether the gain of this retrograde synaptic mechanism is subject to long-term modulation by glutamatergi...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2007
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| 在線閱讀: | https://doi.org/10.1523/jneurosci.3966-06.2007 https://www.jneurosci.org/content/jneuro/27/1/46.full.pdf |
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