Point mutation of glycine receptor α1 subunit in the <i>spasmodic</i> mouse affects agonist responses
Homozygotic spasmodic ( spd/spd ) mice suffer from a motor disorder resembling poisoning by the glycine receptor antagonist strychnine. Here, a point mutation was identified in the glycine receptor α1 subunit gene of the spasmodic mouse which predicts an alanine‐to‐serine exchange at position 52 of...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
1994
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Online Access: | https://doi.org/10.1016/0014-5793(94)00736-5 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2894%2900736-5 |
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