Von Hippel-Lindau (VHL) Inactivation in Sporadic Clear Cell Renal Cancer: Associations with Germline VHL Polymorphisms and Etiologic Risk Factors

Von Hippel-Lindau (VHL) Inactivation in Sporadic Clear Cell Renal Cancer: Associations with Germline VHL Polymorphisms and Etiologic Risk Factors

Renal tumor heterogeneity studies have utilized the von Hippel-Lindau VHL gene to classify disease into molecularly defined subtypes to examine associations with etiologic risk factors and prognosis. The aim of this study was to provide a comprehensive analysis of VHL inactivation in clear cell rena...

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Hlavní autoři: Lee E. Moore, Michael L. Nickerson, Paul Brennan, Jorge R. Toro, Erich Jaeger, Jessica L. Rinsky, Summer S. Han, Давид Заридзе, В. Б. Матвеев, Vladimí­r Janout, Helena Kollárová, Vladimír Bencko, Marie Navrátilová, Neonilia Szeszenia‐Dabrowska, Dana Mateș, Laura S. Schmidt, Petra H. Lenz, Sara Karami, W. Marston Linehan, Maria J. Merino, Stephen J. Chanock, Paolo Boffetta, Wong‐Ho Chow, Frederic M. Waldman, Nathaniel Rothman
Médium: Artigo
Jazyk:angličtina
Vydáno: 2011
On-line přístup:https://doi.org/10.1371/journal.pgen.1002312
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002312&type=printable
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https://doi.org/10.1371/journal.pgen.1002312
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002312&type=printable

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