Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

Mutations in the renal tumour suppressor protein, folliculin, lead to proliferative skin lesions, lung complications and renal cell carcinoma. Folliculin has been reported to interact with AMP-activated kinase, a key component of the mammalian target of rapamycin pathway. Most cancer-causing mutatio...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ravi K. Nookala, Lars Langemeyer, A. Pacitto, Bernardo Ochoa‐Montaño, Jane C. Donaldson, Beata K. Blaszczyk, Dimitri Y. Chirgadze, Francis A. Barr, J. Fernando Bazán, Tom L. Blundell
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2012
Urunga tuihono:https://doi.org/10.1098/rsob.120071
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