Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

Mutations in the renal tumour suppressor protein, folliculin, lead to proliferative skin lesions, lung complications and renal cell carcinoma. Folliculin has been reported to interact with AMP-activated kinase, a key component of the mammalian target of rapamycin pathway. Most cancer-causing mutatio...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Ravi K. Nookala, Lars Langemeyer, A. Pacitto, Bernardo Ochoa‐Montaño, Jane C. Donaldson, Beata K. Blaszczyk, Dimitri Y. Chirgadze, Francis A. Barr, J. Fernando Bazán, Tom L. Blundell
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2012
Rochtain ar líne:https://doi.org/10.1098/rsob.120071
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