Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus

Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus

New neurons generated in the adult dentate gyrus are constantly integrated into the hippocampal circuitry and activated during encoding and recall of new memories. Despite identification of extracellular signals that regulate survival and integration of adult-born neurons such as neurotrophins and n...

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Hlavní autoři: Giorgia Quadrato, Marco Benevento, Stefanie Alber, Carolin Jacob, Elisa M. Floriddia, Tuan Nguyen, Mohamed Y. El‐Naggar, Christine M. Pedroarena, Jeffery D. Molkentin, Simone Di Giovanni
Médium: Artigo
Jazyk:angličtina
Vydáno: 2012
On-line přístup:https://doi.org/10.1073/pnas.1202068109
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