Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

T cells interacting with antigen-presenting cells (APCs) form an "immunological synapse" (IS), a bull's-eye pattern composed of a central supramolecular activation cluster enriched with T cell receptors (TCRs) surrounded by a ring of adhesion molecules (a peripheral supramolecular act...

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Main Authors: Yoshihisa Kaizuka, Adam D. Douglass, Rajat Varma, Michael L. Dustin, Ronald D. Vale
格式: Artigo
语言:英语
出版: 2007
在线阅读:https://doi.org/10.1073/pnas.0710258105
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