Akt Promotes Survival of Cardiomyocytes In Vitro and Protects Against Ischemia-Reperfusion Injury in Mouse Heart

Akt Promotes Survival of Cardiomyocytes In Vitro and Protects Against Ischemia-Reperfusion Injury in Mouse Heart

Background —IGF-1 has been shown to protect myocardium against death in animal models of infarct and ischemia-reperfusion injury. In the present study, we investigated the role of the IGF-1–regulated protein kinase Akt in cardiac myocyte survival in vitro and in vivo. Methods and Results —IGF-1 prom...

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Main Authors:	Yasushi Fujio, Thao Nguyen, Detlef Wencker, Richard N. Kitsis, Kenneth Walsh
格式:	Artigo
语言:	英语
出版:	2000
在线阅读:	https://doi.org/10.1161/01.cir.101.6.660 https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.101.6.660
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