Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study

Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle. Studies from clinical electrophysiology and animal experiments have found that HFpEF is associated with impair...

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Principais autores: Ismail Adeniran, David H. MacIver, Jules C. Hancox, Henggui Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Acesso em linha:https://doi.org/10.3389/fphys.2015.00078
https://www.frontiersin.org/articles/10.3389/fphys.2015.00078/pdf
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