Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study

Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle. Studies from clinical electrophysiology and animal experiments have found that HFpEF is associated with impair...

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Auteurs principaux: Ismail Adeniran, David H. MacIver, Jules C. Hancox, Henggui Zhang
Format: Artigo
Langue:anglais
Publié: 2015
Accès en ligne:https://doi.org/10.3389/fphys.2015.00078
https://www.frontiersin.org/articles/10.3389/fphys.2015.00078/pdf
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