Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study

Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle. Studies from clinical electrophysiology and animal experiments have found that HFpEF is associated with impair...

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Bibliographic Details
Main Authors: Ismail Adeniran, David H. MacIver, Jules C. Hancox, Henggui Zhang
Format: Artigo
Language:English
Published: 2015
Online Access:https://doi.org/10.3389/fphys.2015.00078
https://www.frontiersin.org/articles/10.3389/fphys.2015.00078/pdf
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