Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study

Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle. Studies from clinical electrophysiology and animal experiments have found that HFpEF is associated with impair...

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Autors principals: Ismail Adeniran, David H. MacIver, Jules C. Hancox, Henggui Zhang
Format: Artigo
Idioma:anglès
Publicat: 2015
Accés en línia:https://doi.org/10.3389/fphys.2015.00078
https://www.frontiersin.org/articles/10.3389/fphys.2015.00078/pdf
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