Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer

Significance Papillary thyroid carcinoma (PTC) displays a strong hereditary component that is, in part, due to the additive effects of numerous low-penetrance genes or variants, but virtually no mechanistic information is available. Here, we studied a well-known low-penetrance variant (SNP rs965513)...

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Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Huiling He, Ranran Liu, Sandya Liyanarachchi, Mukund Srinivas, Yanqiang Wang, Keiko Akagi, Yao Wang, Dayong Wu, Qianben Wang, Victor X. Jin, David E. Symer, Rulong Shen, John E. Phay, Rebecca Nagy, Albert de la Chapelle
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2015
Rochtain ar líne:https://doi.org/10.1073/pnas.1506255112
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