Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer
Significance Papillary thyroid carcinoma (PTC) displays a strong hereditary component that is, in part, due to the additive effects of numerous low-penetrance genes or variants, but virtually no mechanistic information is available. Here, we studied a well-known low-penetrance variant (SNP rs965513)...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprog: | engelsk |
Udgivet: |
2015
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Online adgang: | https://doi.org/10.1073/pnas.1506255112 |
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