Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer

Significance Papillary thyroid carcinoma (PTC) displays a strong hereditary component that is, in part, due to the additive effects of numerous low-penetrance genes or variants, but virtually no mechanistic information is available. Here, we studied a well-known low-penetrance variant (SNP rs965513)...

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Main Authors: Huiling He, Ranran Liu, Sandya Liyanarachchi, Mukund Srinivas, Yanqiang Wang, Keiko Akagi, Yao Wang, Dayong Wu, Qianben Wang, Victor X. Jin, David E. Symer, Rulong Shen, John E. Phay, Rebecca Nagy, Albert de la Chapelle
Format: Artigo
Language:English
Published: 2015
Online Access:https://doi.org/10.1073/pnas.1506255112
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https://doi.org/10.1073/pnas.1506255112

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