Glycogen synthase kinase-3β phosphorylates tau protein at multiple sites in intact cells

Hyperphosphorylated tau protein is the major constituent of the paired helical filament (PHF), the major fibrous component of the neurofibrillary lesions of Alzheimer's disease (AD). Hyperphosphorylation of tau is believed to be the critical event that leads to filament assembly. Identification...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Brian R. Sperbera, Susan Leight, Michel Goedert, V. M.-Y. Lee
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 1995
Rochtain ar líne:https://doi.org/10.1016/0304-3940(95)11902-9
Clibeanna: Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!