Aminoglycoside-induced mutation suppression (stop codon readthrough) as a therapeutic strategy for Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is the most common, lethal, X-linked genetic disease, affecting 1 in 3500 newborn males. It is caused by mutations in the DMD gene. Owing to the large size of the gene, the mutation rate in both germline and somatic cells is very high. Nearly 13-15% of DMD cases are...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2010
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| On-line přístup: | https://doi.org/10.1177/1756285610388693 |
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