Alpha-actinin binding kinetics modulate cellular dynamics and force generation
Significance In this study, we examine how proteins that cross-link actin filaments control certain biophysical aspects of living cells. We studied α-actinin-4 (ACTN4) a dimeric rod-shaped homodimer, of particular interest because mutations in its actin binding domain cause a human disease character...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2015
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| Online Access: | https://doi.org/10.1073/pnas.1505652112 |
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