KCC2 activity is critical in limiting the onset and severity of status epilepticus

Significance Status epilepticus (SE) is defined as a state of continuous unremitting seizures that often exhibits underlying deficits in neuronal inhibition mediated by GABA A receptors. The efficacy of neuronal inhibition is critically dependent on the activity of the K + /Cl – cotransporter KCC2,...

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Main Authors: Liliya Silayeva, Tarek Z. Deeb, Rochelle M. Hines, Matt R. Kelley, Michaelanne B. Munoz, Henry H.C. Lee, Nicholas J. Brandon, John Dunlop, Jaime L. Maguire, Paul Davies, Stephen J. Moss
Format: Artigo
Jezik:angleščina
Izdano: 2015
Online dostop:https://doi.org/10.1073/pnas.1415126112
https://www.pnas.org/content/pnas/112/11/3523.full.pdf
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