KCC2 activity is critical in limiting the onset and severity of status epilepticus
Significance Status epilepticus (SE) is defined as a state of continuous unremitting seizures that often exhibits underlying deficits in neuronal inhibition mediated by GABA A receptors. The efficacy of neuronal inhibition is critically dependent on the activity of the K + /Cl – cotransporter KCC2,...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2015
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| Online Access: | https://doi.org/10.1073/pnas.1415126112 https://www.pnas.org/content/pnas/112/11/3523.full.pdf |
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