KCC2 activity is critical in limiting the onset and severity of status epilepticus

KCC2 activity is critical in limiting the onset and severity of status epilepticus

Significance Status epilepticus (SE) is defined as a state of continuous unremitting seizures that often exhibits underlying deficits in neuronal inhibition mediated by GABA A receptors. The efficacy of neuronal inhibition is critically dependent on the activity of the K + /Cl – cotransporter KCC2,...

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Main Authors:	Liliya Silayeva, Tarek Z. Deeb, Rochelle M. Hines, Matt R. Kelley, Michaelanne B. Munoz, Henry H.C. Lee, Nicholas J. Brandon, John Dunlop, Jaime L. Maguire, Paul Davies, Stephen J. Moss
Formato:	Artigo
Idioma:	inglés
Publicado:	2015
Acceso en liña:	https://doi.org/10.1073/pnas.1415126112 https://www.pnas.org/content/pnas/112/11/3523.full.pdf
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