Large deletions of the APC gene in 15% of mutation‐negative patients with classical polyposis (FAP): A Belgian study

Germline mutations of the APC gene are responsible for familial adenomatous polyposis (FAP). Most of the mutations are protein truncating mutations and are spread over the coding region. Rare whole-gene deletions or exonic deletions have been described. From a series of 85 patients clinically diagno...

全面介绍

Saved in:
书目详细资料
Main Authors: G Michils, Sabine Tejpar, Ronald Thoelen, Eric Van Cutsem, Joris Vermeesch, Jean‐Pierre Fryns, Eric Legius, Gert Matthijs
格式: Artigo
语言:英语
出版: 2005
在线阅读:https://doi.org/10.1002/humu.20122
标签: 添加标签
没有标签, 成为第一个标记此记录!